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Irritable bowel syndrome (IBS) is a gastrointestinal (GI) disorder that causes symptoms like abdominal pain and bloating, as well as bowel movement changes like diarrhea, constipation, or both. For many people, IBS symptoms can disrupt daily routines and diminish their quality of life.
IBS is a functional gastrointestinal disorder, meaning it affects the function of the digestive system but does not cause structural changes or inflammation. Experts have not identified a definitive cause for IBS, but a combination of factors likely plays a role in its development.
Theories
What causes IBS is not fully understood, but researchers have several theories about the underlying mechanisms that contribute to its development.
The main belief is that IBS is a disorder of how the brain and gut work together. However, there are other factors besides a gut-brain interaction that could cause IBS.
Growing evidence suggests that IBS may develop due to abnormalities in gut microbiota makeup, gut motility, and immune system function. The role each of these factors plays in IBS varies from person to person.
International Foundation for Gastrointestinal Disorders. What causes IBS?.